The Division of Orthopaedic Surgery in partnership with the other program
elements of the Musculoskeletal Health and Arthritis Program aims to
establish a longitudinal patient database of patients affected by
osteoarthritis.
The establishment of this database will involve the collection of extensive
demographic, clinical outcomes, and quality of life data on patients with
osteoarthritis. In addition, this initiative involves the collection and
banking blood for DNA and disease biomarkers, as well as cartilage, synovium
and synovial fluid collected at set intervals.
Once established, the biobank will be integrated with a database platform,
to allow for systematic study of genetic, environmental and mechanical
processes which impact disease course, outcome and response to treatment.
The goal of the biobank and longitudinal database is to discover the cause
of the osteoarthritis, develop early diagnostic tests and develop novel
therapeutic interventions.
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